After registering a four-wicket win in the first T20I, India on Sunday secured a 22-run win by the DLS method in the second T20I in Florida, thereby clinching the series.
After Sunday's win, skipper Virat Kohli hinted that he might experiment with the line-up in Tuesday's game.
"Winning is always going to be a priority. But sealing the series gives the chance to bring few guys in. Idea is always going to be to win first. But winning the first two games, gives the cushion," skipper Kohli had said.
Chahar brothers, Deepak and Rahul, and Shreyas Iyer who till now haven't got a chance to play are likely to get a place in the playing XI in Guyana.
With wicketkeeper Rishabh Pant failing in the first two matches, it might be possible that K.L. Rahul could be roped in his place. Also, Bhuvneshwar Kumar could be rested to give Deepak a crack while Rahul could replace either Krunal Pandya or Washington Sundar.
On the other hand, Windies who have already lost the series will look to play for lost pride and end the three-match rubber on a high, before taking on the Men in Blue in the three ODIs and the subsequent two-Test series.
India: Virat Kohli (Captain), Rohit Sharma, Shikhar Dhawan, KL Rahul, Shreyas Iyer, Manish Pandey, Rishabh Pant (wicket-keeper), Krunal Pandya, Ravindra Jadeja, Washington Sundar, Rahul Chahar, Bhuvneshwar Kumar, Khaleel Ahmed, Deepak Chahar, Navdeep Saini
West Indies: John Campbell, Evin Lewis, Shimron Hetmyer, Nicholas Pooran, Kieron Pollard, Rovman Powell, Carlos Brathwaite, Keemo Paul, Sunil Narine, Sheldon Cottrell, Oshane Thomas, Anthony Bramble, Andre Russell, Khary Pierre.
( With inputs from IANS )