American college of surgeons - Latest News Update, Information, Photos & Videos on American college of surgeons at Lokmat Times

Saying that critically ill COVID-19 patients may be at high risk for developing renal failure, venous blood clots, and other complications associated with blood clots, such as stroke, researchers have emphasised on the need for early screening.Thromboelastography (TEG) is a whole blood assay that provides a broad picture of how an individual patient's blood forms clots, including how long clotting takes, how strong clots are, and how soon clots break down.TEG is highly specialised and used primarily by surgeons and anesthesiologists to evaluate the efficiency of blood clotting; it is not widely used in other clinical settings."The COVID-19 pandemic is opening doors for multidisciplinary collaboration so trauma acute care surgeons and intensivists can bring the tools they use in their day-to-day lives and apply them in the critical care setting to new problems," said Franklin Wright, Assistant Professor of Surgery at the University of Colorado School of Medicine in the US.The researchers evaluated outcomes for all patients who had a TEG assay as part of their treatment for COVID-19 infection as well as other conventional coagulation assays, including ones that measure D-dimer levels.D-dimer is a protein fragment that is produced when a blood clot dissolves. D-dimer levels are elevated when large numbers of clots are breaking down.A total of 44 patients treated for COVID-19 infection between March 22 and April 20 were included in the analysis.Those whose bodies were not breaking down clots most often required hemodialysis and had a higher rate of clots in the veins.These patients were identified by TEG assays showing no clot breakdown after 30 minutes and a D-dimer level greater than 2600 ng/mL (nanograms per millilitre).Eighty per cent of patients with both affirmative test findings were placed on dialysis compared with 14 per cent who tested for neither finding.Patients with affirmative test findings also had a 50 per cent rate of venous blood clots compared with zero per cent for those patients with neither finding."These study results suggest there may be a benefit to early TEG testing in institutions that have the technology to identify COVID-19 patients who may need more aggressive anticoagulation therapy to prevent complications from clot formation," Wright said.Their research was published as an "article in press" on the Journal of the American College of Surgeons website ahead of print.The research team is now participating in a randomized clinical trial of a drug that breaks down blood clots in COVID-19-infected patients."This is an early step on the road to discovering treatments to prevent some of the complications that come with this disease," said Wright who is lead author of the research article.Patients with COVID-19 infection are being enrolled in a randomized clinical trial of tissue plasminogen activator (tPA).This drug is a natural anticoagulant that was approved by the US Food and Drug Administration in 1996 for the treatment of diseases associated with clotting disorders, such as heart attack, stroke, and pulmonary embolism.The trial will assess the efficacy and safety of intravenous tPA in improving respiratory function and management of patients with aggressive blood clotting."This study suggests that testing whole blood clotting measurements may allow physic to identify and treat patients with COVID-19 more effectively to prevent complications and encourage further research into therapies to prevent blood clots in these patients," Wright said.( With inputs from IANS )

Home

City

Latest News

Cricket

LT Premium

National

International

Maharashtra

Opinions

Chhatrapati Sambhajinagar

Nagpur

Entertainment

Photos

Business

Technology

Sports

Lifestyle

Social Viral

Lokmat Games

Health

Lok Sabha Election 2024

Ram Navami 2024

Dubai Rains

Maharashtra Lok Sabha Election

IPL 2024

Salman Khan

American College Of SurgeonsFOLLOW

American college of surgeons, Latest News

Health :Research: Colorectal cancer patients can benefit from timely surveillance with chest imaging

According to new research presented at the Scientific Forum of the American College of Surgeons (ACS) Clinical Congress 2022, colorectal cancer patients with certain clinical characteristics may benefit from more frequent chest imaging to help identi ...

Health :Clinical outcomes in post surgery patients linked to hospital room features: Study

The findings of recent research suggest that certain hospital room features, such as having a window view and distance from a nursing station, may influence clinical outcomes after undergoing high-risk operations. ...

Health :Research discovers antibiotics for treating appendicitis

According to the findings of the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) trial and an updated treatment guideline for appendicitis from the American College of Surgeons, antibiotics are now an accepted first-line treatment for ...

Health :Research approves antibiotics for appendicitis

According to final results of the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) trial, and an updated treatment guideline for appendicitis from the American College of Surgeons, antibiotics are now an accepted first-line treatment fo ...

Health :Surgery is viable treatment for pancreatic cancer patients especially after chemotherapy, says study

Patients with stage 2 pancreatic cancer who receive chemotherapy followed by resection live nearly twice as long as patients who receive only chemotherapy, according to a study drove by the Journal of the American College of Surgeons. ...

Health :Screen COVID-19 patients for blood clotting abnormalities: Study

Saying that critically ill COVID-19 patients may be at high risk for developing renal failure, venous blood clots, and ... ...