| Name | Duration | Party |
|---|
| Edappadi K Palaniswami | February 16, 2017 - Present | AIADMK |
| O. Panneerselvam | Dec 6, 2016 - Feb 16, 2017 | AIADMK |
| J. Jayalalithaa | May 19, 2016 - Dec 5, 2016 | AIADMK |
| J. Jayalalithaa | May 23, 2015 - May 19, 2016 | AIADMK |
| O Panneerselvam | 29th Sep 2014 - May 23, 2015 | AIADMK |
| J. Jayalalithaa | 16. May. 2011 - - | AIADMK |
| M. Karunanidhi | 13. May. 2006 - 15. May. 2011 | |
| J. Jayalalithaa | Mar 2, 2002 - 12. May. 2006 | AIADMK |
| O. Panneerselvam | Sep 21, 2001 - Mar 1, 2002 | AIADMK |
| J. Jayalalithaa | 14. May. 2001 - Sep 21, 2001 | AIADMK |
| M. Karunanidhi | 13. May. 1996 - 13. May. 2001 | DMK |
| J. Jayalalithaa | Jun 24, 1991 - 12. May. 1996 | AIADMK |
| President's rule | Jan 30, 1991 - Jun 24, 1991 | |
| M. Karunanidhi | Jan 27, 1989 - Jan 30, 1991 | DMK |
| President's rule | Jan 30, 1988 - Jan 27, 1989 | |
| Janaki Ramachandran | Jan 7, 1988 - Jan 30, 1988 | AIADMK |
| V.R. Nedunchezhiyan (acting) | Dec 24, 1987 - Jan 7, 1988 | AIADMK |
| M. G. Ramachandran | Feb 10, 1985 - Dec 24, 1987 | AIADMK |
| M. G. Ramachandran | Jun 9, 1980 - Nov 15, 1984 | AIADMK |
| President's rule | Feb 17, 1980 - Jun 9, 1980 | |
| M. G. Ramachandran | Jun 30, 1977 - Feb 17, 1980 | AIADMK |
| President's rule | Jan 31, 1976 - Jun 30, 1977 | |
| M. Karunanidhi | Mar 15, 1971 - Jan 31, 1976 | DMK |
| M. Karunanidhi | Feb 10, 1969 - Jan 4, 1971 | DMK |
| V.R. Nedunchezhiyan (acting) | Feb 3, 1969 - Feb 10, 1969 | DMK |
| C. N. Annadurai | Jan 14, 1969 - Feb 3, 1969 | DMK |
| C. N. Annadurai | Mar 6, 1967 - Jan 14, 1969 | DMK |
| M. Bakthavatsalam | Oct 2, 1963 - Mar 6, 1967 | INC |
| K. Kamaraj | Mar 15, 1962 - Oct 2, 1963 | INC |
| K. Kamaraj | Apr 13, 1957 - Mar 1, 1962 | INC |
| K. Kamaraj | Apr 13, 1954 - Mar 31, 1957 | INC |
| C. Rajagopalachari | Apr 10, 1952 - Apr 13, 1954 | INC |
| P. S. Kumaraswamy Raja | Jan 26, 1950 - Apr 9, 1952 | INC |
