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Translumina, a global developer and manufacturer of innovative cardiovascular medical devices used in interventional cardiology and minimally invasive surgery, announced that Journal of the American College of Cardiology (JACC), which is amongst the top publications in the world for cardiology with a high impact factor as per Journal Citation Reports, has published ten-year follow-up data on its dual-drug polymer-free Drug Eluting stent (DES) VIVO ISAR last week describing its excellent efficacy and safety profile.Many studies have proven that polymers are pro-inflammatory and may cause stent thrombosis. However, the use of polymers has been necessary for current-generation DES as they control the release kinetics of the drug by acting as a carrier for drug loading and release.VIVO ISAR is the first technology that uses Probucol, an antioxidant and lipid-lowering drug, as a carrier for releasing Sirolimus (an anti-restenotic drug) and thus creates for a polymer-free DES platform."The ten-year result of VIVO ISAR is a major breakthrough in DES technology as it proves that synthetic polymers can be removed from a DES without compromising the efficacy of the DES. The excellent safety profile proved over ten years also reassures the cardiologist for the longevity of the clinical results for treating complex coronary artery disease in high-risk patient subsets. This DES technology carries the great potential of significantly shortening the duration of dual antiplatelet therapy," said Dr Adnan Kastrati, Director, Cardiac Cath Lab, German Heart Centre, Munichand also the lead investigator of ISAR TEST 5, the trial that compared VIVO ISAR to Endeavour Resolute (Medtronic Inc USA)."It is a proud moment for Translumina as we become the first company in the world to present ten-year data for two breakthrough DES technologies which have redefined the paradigms of safety and efficacy. With polymer-free VIVO ISAR, we are pioneers of third-generation DES where doctors will not be required to prescribe long antiplatelet therapies to patients undergoing PCI to overcome the ill effects of polymers as seen in first and second-generation DES," said Gurmit Singh Chugh, MD, and Co-founder, Translumina.In 2018, Translumina became the first company in the world to present ten-year follow-up data on its biodegradable polymer DES, Yukon Choice PC, in a head-to-head study against Xience (Abbott Inc USA).The study, called ISAR-TEST 4 trial, was presented at the 2018 American Heart Association meeting and was simultaneously published in circulation.Everstone Capital invested in Translumina in 2019 to further strengthen its research & development pipeline, scale its manufacturing operations, and expand its global footprint to transform Translumina into a leading multinational medical devices company.This story is provided by PRNewswire. will not be responsible in any way for the content of this article. (/PRNewswire)( With inputs from ANI )

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Gurmit singh chugh, Latest News

Business :Translumina further strengthens Its technology portfolio with acquisition of Blue Medical Devices, Netherlands

PRNewswire New Delhi [India]/Helmond [Netherlands], June 29: Translumina, a global leader in Interventional Cardiovascular medical devices with manufacturing presence ... ...

Business :Translumina bolsters its German presence with acquisition of Lamed GmbH

PRNewswire New Delhi [India]/ Munich [Germany], June 7: Translumina, a global leader in interventional cardiovascular medical devices with manufacturing ... ...

Business :Translumina launches VIVO ISAR, its Dual-Drug Polymer-free Coated Stent (DDCS) in International markets

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Business :Journal of the American College of Cardiology publishes 10-year safety and efficacy data on VIVO ISAR, Translumina's polymer-free drug-eluting stent

Translumina, a global developer and manufacturer of innovative cardiovascular medical devices used in interventional cardiology and minimally invasive surgery, announced that Journal of the American College of Cardiology (JACC), which is amongst the ...